Product Description
Phylogenetic Trees Made Easy helps thereader get started in creating phylogenetic trees from protein ornucleic acid sequence data. Although aimed at molecular and cellbiologists, who may not be familiar with phylogenetic or evolutionarytheory, it also serves students who may be familiar with phylogenetictheory but are unfamiliar with the tools used to apply that theory. Thereader is led, step by step, through identifying sequences that arehomologous to a sequence of interest, downloading these sequences fromdatabases, creating multiple alignments, and using several differentmethods to construct trees. Learn More boxes present background on thevarious concepts and methods, and a website provides files needed forworking through the tutorials in the text as well as additionalsoftware that facilitates some of the methods discussed. Key Changes tothe Third Edition: * Over 90% of the text and screenshots are new. * Anew program, MEGA, that has dramatically simplified and sped up themost tedious parts of making trees searching for and downloadingsequences, aligning those sequences, and getting them into suitableformats is introduced as the primary tool for constructing trees. *PHYML, another new program that has sped up the Maximum Likelihoodmethod by more than 100-fold, making it a practical alternative toother methods, is introduced. * Chapter 9 is devoted to a detailedmethod for reconstructing very ancient ancestral sequences, andsoftware to facilitate that method is made available on the website. *Chapter 10 speaks to detecting adaptive evolution. * The final chaptercomprises detailed instructions for working with programs on Macintosh,Windows, and Unix platforms.
- Paperback: 233 pages
- Publisher: Sinauer Associates, Inc.; 3 edition (June 18, 2007)
- Language: English
- ISBN-10: 0878933107
地址：
http://www.amazon.com/Phylogenetic-Trees-Made-Easy-How/dp/0878933107/
2007年的新版图书。
